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      Calc Function

    • Calcs that help predict probability of a diseaseDiagnosis
    • Subcategory of 'Diagnosis' designed to be very sensitiveRule Out
    • Disease is diagnosed: prognosticate to guide treatmentPrognosis
    • Numerical inputs and outputsFormula
    • Med treatment and moreTreatment
    • Suggested protocolsAlgorithm

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    Attention COACH STUDY participants:

    The principal investigators of the study request that you use the official version of the modified score here.
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    Revised Original Score for Autoimmune Hepatitis (AIH)

    Revised version of the original scoring system for the diagnosis of autoimmune hepatitis.
    When to Use
    Why Use

    Patients with established hepatitis and available liver biopsy results, but unclear diagnosis.

    AIH is multifactorial, complex, and typically has many competing diagnoses. The score offers a data driven, consensus-based path to help guide treatment.

    Male
    0
    Female
    +2
    <1.5
    +2
    1.5-3.0
    0
    >3.0
    -2
    >2.0
    +3
    1.5-2.0
    +2
    1.0-1.5
    +1
    <1.0
    0
    >1:80
    +3
    1:80
    +2
    1:40
    +1
    <1:40
    0
    Seropositivity for other defined autoantibodies
    +2
    HLA-DR3 or HLA-DR4
    +1
    None of the above
    0
    Positive
    -4
    Negative
    0
    Positive
    -3
    Negative
    +3
    Yes
    -4
    No
    +1
    <25 g/day
    +2
    25-60 g/day
    0
    >60 g/day
    -2
    Yes
    +3
    No
    0
    Yes
    +1
    No
    0
    Yes
    +1
    No
    0
    Yes
    -3
    No
    0
    Yes
    -3
    No
    0
    Yes
    +2
    No
    0
    Complete
    +2
    Relapse
    +3

    Result:

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    Next Steps
    Evidence
    Creator Insights
    Dr. Fernando Alvarez

    About the Creator

    Fernando Alvarez, MD, is the Chief of the Division of Gastroenterology, Hepatology & Nutrition at CHU Sainte-Justine, University of Montreal. He studied medicine in his home country of Argentina, where he focused on hepatology and pediatrics. He currently practices pediatric hepatology, and he researches topics including autoimmune hepatitis, viral hepatitis, and liver immunity.

    To view Dr. Fernando Alvarez's publications, visit PubMed

    Are you Dr. Fernando Alvarez? Send us a message to review your photo and bio, and find out how to submit Creator Insights!
    MDCalc loves calculator creators – researchers who, through intelligent and often complex methods, discover tools that describe scientific facts that can then be applied in practice. These are real scientific discoveries about the nature of the human body, which can be invaluable to physicians taking care of patients.
    About the Creator
    Dr. Fernando Alvarez
    Are you Dr. Fernando Alvarez?