Calc Function

    • Calcs that help predict probability of a diseaseDiagnosis
    • Subcategory of 'Diagnosis' designed to be very sensitiveRule Out
    • Disease is diagnosed: prognosticate to guide treatmentPrognosis
    • Numerical inputs and outputsFormula
    • Med treatment and moreTreatment
    • Suggested protocolsAlgorithm





    Chief Complaint


    Organ System


    Patent Pending

    Rome II Diagnostic Criteria for Irritable Bowel Syndrome (IBS)

    Provides criteria for diagnosis of irritable bowel syndrome (IBS) within 3 month period.


    The Rome IV Criteria are now recommended as an update to these criteria (May 2016).
    When to Use
    Why Use

    Patients being evaluated for possible IBS.

    The Rome II Criteria, developed through a literature review and consensus process, defined the diagnosis of Irritable Bowel Syndrome (IBS) until the Rome III and subsequently Rome IV Criteria refined them. There remains no objective reference (i.e., ‘gold standard’) for the diagnosis.

    The symptoms that define IBS are generally subjective and self-reported, making a classification system helpful. Moreover, there is some evidence to support the notion that patients who meet formal Rome criteria are more likely to respond to some therapies.

    Patient must have at least 12 weeks of abdominal discomfort or pain, which need not be consecutive, in the preceding 12 months with at least 2 of following 3 features:


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    Next Steps
    Creator Insights


    The Rome Criteria are helpful in classifying patients and for determining potential therapies.


    We are unaware of validated management algorithms using the Rome Criteria.

    Critical Actions

    IBS is a ‘rule-out’ diagnosis, which is to say all other possibilities must be ruled out first.

    Dr. Douglas Drossman

    About the Creator

    Douglas Drossman, MD, is professor emeritus of medicine and psychiatry at the University of North Carolina School of Medicine. He is also the founder of the Drossman Center for the Education and Practice of Biopsychosocial Care and Drossman Consulting, LLC. Dr. Drossman has written over 500 articles and book chapters, has published two books, a GI procedure manual and a textbook of functional GI disorders (Rome I-IV), and serves on six editorial and advisory boards.

    To view Dr. Douglas Drossman's publications, visit PubMed

    About the Creator
    Dr. Douglas Drossman