This is an unprecedented time. It is the dedication of healthcare workers that will lead us through this crisis. Thank you for everything you do.

      Calc Function

    • Calcs that help predict probability of a diseaseDiagnosis
    • Subcategory of 'Diagnosis' designed to be very sensitiveRule Out
    • Disease is diagnosed: prognosticate to guide treatmentPrognosis
    • Numerical inputs and outputsFormula
    • Med treatment and moreTreatment
    • Suggested protocolsAlgorithm

    Disease

    Select...

    Specialty

    Select...

    Chief Complaint

    Select...

    Organ System

    Select...

    Patent Pending

    Rome IV Diagnostic Criteria for Dyspepsia

    Provides criteria for diagnosis of dyspepsia.

    INSTRUCTIONS

    • Use in patients with recurrent upper GI symptoms on average once weekly in the last 3 months with symptom onset ≥6 months ago and no abnormalities on diagnostic testing, including upper endoscopy.
    • Do NOT use in patients with alarm symptoms such as GI bleeding, unexplained iron deficiency anemia, unintentional weight loss, palpable abdominal mass, family history of colon cancer or symptom onset ≥50 years of age and not yet screened for colon cancer, or sudden/acute onset of new change in bowel habit.
    When to Use
    Pearls/Pitfalls
    Why Use
    • Patients with recurrent upper GI symptoms on average once weekly in the last 3 months with symptom onset ≥6 months ago and no abnormalities on diagnostic testing, including upper endoscopy.
    • Do NOT use in patients with alarm symptoms such as:
      • Unexplained iron deficiency anemia.
      • Signs or symptoms of gastrointestinal bleeding.
      • Unintentional weight loss.
      • Palpable abdominal mass or lymphadenopathy on exam.
      • Family history of colon cancer and have not had age-appropriate colon cancer screening.
      • Onset of symptoms age ≥50 years and have not had age-appropriate colon cancer screening.
      • Sudden or acute onset of new change in bowel habit.

    • Developed to diagnose functional dyspepsia in patients presenting with upper GI tract symptoms.  

    • A diagnosis of functional dyspepsia can only be made when there is no evidence of organic, systemic, or metabolic disease to explain the symptoms. This includes workup with upper endoscopy and evaluation for the presence of Helicobacter pylori infection (and treatment if positive).

    • There are two subtypes of functional dyspepsia: post-prandial distress syndrome and epigastric pain syndrome. These criteria are used to differentiate between the two.

    • Helps to make a diagnosis when standard workup of upper gastrointestinal tract symptoms is negative.

    • Helps guide conversations with patients about the diagnosis of functional dyspepsia and typical symptoms.

    • May help guide management of functional dyspepsia based on subtype (post-prandial distress syndrome vs. epigastric pain syndrome).

    Must have ≥1 of the following

    For 3 months prior with symptom onset ≥6 months ago

    Must also have the following:

    Diagnostic Result:

    Please fill out required fields.

    Next Steps
    Evidence
    Creator Insights
    Dr. Douglas Drossman

    About the Creator

    Douglas Drossman, MD, is professor emeritus of medicine and psychiatry at the University of North Carolina School of Medicine. He is also the founder of the Drossman Center for the Education and Practice of Biopsychosocial Care and Drossman Consulting, LLC. Dr. Drossman has written over 500 articles and book chapters, has published two books, a GI procedure manual and a textbook of functional GI disorders (Rome I-IV), and serves on six editorial and advisory boards.

    To view Dr. Douglas Drossman's publications, visit PubMed

    Are you Dr. Douglas Drossman? Send us a message to review your photo and bio, and find out how to submit Creator Insights!
    MDCalc loves calculator creators – researchers who, through intelligent and often complex methods, discover tools that describe scientific facts that can then be applied in practice. These are real scientific discoveries about the nature of the human body, which can be invaluable to physicians taking care of patients.
    Content Contributors
    • Colleen Parker, MD
    About the Creator
    Dr. Douglas Drossman
    Are you Dr. Douglas Drossman?
    Content Contributors
    • Colleen Parker, MD