This is an unprecedented time. It is the dedication of healthcare workers that will lead us through this crisis. Thank you for everything you do.

      Calc Function

    • Calcs that help predict probability of a diseaseDiagnosis
    • Subcategory of 'Diagnosis' designed to be very sensitiveRule Out
    • Disease is diagnosed: prognosticate to guide treatmentPrognosis
    • Numerical inputs and outputsFormula
    • Med treatment and moreTreatment
    • Suggested protocolsAlgorithm





    Chief Complaint


    Organ System


    Patent Pending

    Rome IV Diagnostic Criteria for Irritable Bowel Syndrome (IBS)

    Provides criteria for diagnosis of irritable bowel syndrome.


    Use in patients with recurrent abdominal pain at least 1 day per week in the last 3 months on average, associated with ≥2 of the criteria below. The criteria are fulfilled with symptoms onset 6 months prior to diagnosis.

    When to Use

    Patients being evaluated for possible IBS.

    How Rome IV has changed from Rome III:

    • Intended to be applied to a more multicultural population than Rome III, which was derived for a Western cohort.
    • Requires only pain as a symptom (“discomfort” has been eliminated because it is nonspecific). Pain can either increase or decrease with bowel movements, versus decreasing only in Rome III.
    • Includes criteria for subtypes of IBS.

    Point to keep in mind:

    • There remains no objective reference (i.e., “gold”) standard for IBS; the criteria were developed through a literature review and consensus process.
    Must have ≥2 of the following:

    Associated with recurrent abdominal pain ≥1 day/wk in the last 3 months (on average)

    Diagnostic Result:

    Please fill out required fields.

    Next Steps
    Creator Insights
    Dr. Douglas Drossman

    About the Creator

    Douglas Drossman, MD, is professor emeritus of medicine and psychiatry at the University of North Carolina School of Medicine. He is also the founder of the Drossman Center for the Education and Practice of Biopsychosocial Care and Drossman Consulting, LLC. Dr. Drossman has written over 500 articles and book chapters, has published two books, a GI procedure manual and a textbook of functional GI disorders (Rome I-IV), and serves on six editorial and advisory boards.

    To view Dr. Douglas Drossman's publications, visit PubMed

    Are you Dr. Douglas Drossman? Send us a message to review your photo and bio, and find out how to submit Creator Insights!
    MDCalc loves calculator creators – researchers who, through intelligent and often complex methods, discover tools that describe scientific facts that can then be applied in practice. These are real scientific discoveries about the nature of the human body, which can be invaluable to physicians taking care of patients.
    About the Creator
    Dr. Douglas Drossman
    Are you Dr. Douglas Drossman?