Calc Function

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    • Subcategory of 'Diagnosis' designed to be very sensitiveRule Out
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    Patent Pending

    SEDAN Score for Post-tPA Hemorrhage

    Predicts risk of Symptomatic Intracerebral Hemorrhage (sICH) after tPA.
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    BEFORE USE

    Applies to patients not undergoing endovascular treatment, tPA within 4.5 hours.

    When to Use
    Pearls/Pitfalls
    Why Use

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    Creator Insights

    Advice

    • Consider tPA contraindications closely, as institutions may have slightly different definitions of contraindications (absolute and relative).
    • tPA for stroke should only be given in conjunction with Neurology consultation and after extensive discussion with the patient and family about risk and benefit.
    • Patients receiving tPA should be monitored in an ICU setting.
    • Even in low-risk patients, patients with changing neurologic exams or mental status should receive emergent re-imaging to assess for sICH.
    • Consider other bleeding sites (GI, GU, for example) in post-tPA patients and exercise caution with even minimally invasive procedures such as venipuncture or foley catheter placement.