THRIVE Score for Stroke Outcome
The THRIVE score can help physicians predict several key outcomes in patients suffering an ischemic stroke.
The Total Health Risk In Vascular Events (THRIVE) score uses NIHSS score, age, and chronic disease to predict long-term neurologic outcomes in stroke patients.
- Scored on a 0-9 point scale, lower is better.
- A score of 0 predicts a 79-88% chance of a good neurological outcome and 0-2% predicted mortality at 90 days.
- A score of 9 predicts a 7-16% chance of a good neurological outcome and 38-58% mortality at 90 days.
- Note: A newer outcome measure is now performed using the THRIVE-c calculation, which uses continuous age and NIHSS to more accurately determine outcome probability.
- Risk of hemorrhagic conversion increases proportionally for each additional point in the THRIVE score.
- The THRIVE score performs well when applied to stroke patients who received IV tPA as well as patients who did not receive thrombolysis or endovascular intervention.
Points to keep in mind:
- The THRIVE score has been validated only retrospectively in various stroke databases and has not been applied prospectively.
There are nearly 800,000 cases of acute stroke in the United States every year, with 130,000 associated deaths (4th leading cause of death in Americans).
The THRIVE score can help physicians predict functional outcome, death after stroke, and the risk of brain hemorrhage after IV tPA administration in patients who suffer an ischemic stroke.