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    US (MEDPED) Diagnostic Criteria for Familial Hypercholesterolemia (FH)

    Diagnoses familial hypercholesterolemia using age, family history, and total cholesterol.
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    Why Use

    Patients with suspected familial hypercholesterolemia (FH), including those with elevated cholesterol and/or personal or family history of premature cardiac events.

    Uses three easily obtainable parameters to diagnose familial hypercholesterolemia.

    • FH is underdiagnosed and carries significant mortality risk from cardiac events.
    • Alternative diagnostic criteria include the Dutch Criteria and the Simon Broome Diagnostic Criteria. Of the three, MEDPED is the only one that does not require genetic testing for diagnosis.
    • The risk factors in each criteria set are similar, and clinical judgment as well as local practice factors (similarity of target population to study population) should be considered.
    <20
    20-29
    30-39
    >40
    1st Degree
    2nd Degree
    3rd Degree
    mg/dL

    Result:

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    Next Steps
    Evidence
    Creator Insights

    Advice

    Consider lifestyle changes, drug therapy, family testing, and other measures to manage FH if diagnosed.

    About the Creator
    Dr. Roger R. Williams
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