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    Winters' Formula for Metabolic Acidosis Compensation

    Calculates the expected pCO₂ compensation in a purely metabolic acidosis.
    When to Use
    Why Use
    • A patient with a suspect pure metabolic acidosis.
    • A patient with a mixed acidosis to determine level of compensation.

    In a compensated state, a patient with a metabolic acidosis should be able to compensate by developing a respiratory alkalosis. Winters' Formula predicts this level of “appropriate” compensation.



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    Creator Insights


    • Users may be interested in the MDCalc ABG Analyzer which can attempt to assess for different forms of acid-base disorders.
    • The Anion Gap calculator can also help determine the type of acidosis (gap vs non-gap).
    Dr. August Supervia

    About the Creator

    August Supervia, MD, is a practicing physician in the emergency department at Hospital Universitari del Mar in Barcelona, Spain. He is an active researcher and a member of the European Respiratory Society.

    To view Dr. August Supervia's publications, visit PubMed

    About the Creator
    Dr. August Supervia