Calc Function

  • Diagnosis
  • Rule Out
  • Prognosis
  • Formula
  • Treatment
  • Algorithm
  • Disease
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    Specialty
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    Chief Complaint
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    Organ System
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    Definitive and Adjuvant Radiotherapy in Locally Advanced Non-Small Cell Lung Cancer (LA NSCLC)(beta)

    Based on guidelines from the American Society for Radiation Oncology, also endorsed by ASCO.

    Treatment - Unresectable LA NSCLC

    Role and Timing of Radiotherapy

    Strong recommendation
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    High quality evidence

    Strong recommendation
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    High quality evidence

    Strong recommendation
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    High quality evidence

    Strong recommendation
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    Moderate quality evidence

    Strong recommendation
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    Low quality evidence

    Strong recommendation
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    N/A

    Dose of Radiotherapy

    Strong recommendation
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    High quality evidence

    Strong recommendation
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    Moderate quality evidence

    Strong recommendation
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    Moderate quality evidence

    Treatment - Resected LA NSCLC

    Role of Postoperative Radiotherapy

    Strong recommendation
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    Moderate quality evidence

    Strong recommendation
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    Moderate quality evidence

    Trimodality Treatment

    Role of Radiotherapy

    Strong recommendation
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    High quality evidence

    Strong recommendation
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    Moderate quality evidence

    Strong recommendation
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    Moderate quality evidence

    How strong is the ASTRO's recommendation?

    Strong recommendation
    The panel was very confident that the benefits of the intervention clearly outweighed the harms.
    Conditional recommendation
    The evidence indicates that there is no apparent net benefit or harm or when the balance between benefits and risks/burden is unclear.
    High quality evidence
    We are very confident that the true effect lies close to that of the estimate of the effect.
    Moderate quality evidence
    We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different.
    Low quality evidence
    Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect.
    N/A
    No evidence was assigned.