MDCalc

Subtle Anterior STEMI Calculator (4-Variable)

Differentiates normal variant ST elevation (benign early repolarization) from anterior STEMI, more sensitive than 3-variable version.

Note: this calculator replaces the older 3-variable version and is recommended by MDCalc and Dr. Stephen Smith. Before using this calculator, make sure the EKG shows ≥1 mm ST elevation (STE) in ≥1 of the precordial leads V2-V4. If it shows any one of the following, then it is NOT normal variant, and is very likely to be LAD occlusion; such cases were excluded from the study as "obvious" MI:

  • >5 mm STE.
  • Non-concave STE.
  • Inferior reciprocal changes.
  • Anterior ST depression.
  • Terminal QRS distortion in V2 or V3:
  • Q waves in any of V2 to V4.
  • Any T wave inversion from V2 to V6.
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Result:

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Advice
  • Cath lab activation is appropriate in Smith-positive patients, in the proper clinical context. At the very least, it should prompt very frequent serial EKGs and echocardiography.
  • The formula is best used to identify patients with LAD occlusion initially thought to have normal variant early repolarization. 
  • If results indicate negative for STEMI, proceed with caution if STEMI was otherwise suspected.