Rome IV Diagnostic Criteria for Globus
Official Rome IV criteria for the diagnosis of globus.
Use in patients with symptoms suggestive of globus, such as a persistent or intermittent non-painful sensation of a lump or foreign body in the throat, for at least 6 months.
Patients with any of the following features must be evaluated clinically for other diagnoses even though globus may be present:
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Dysphagia.
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Odynophagia.
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Sore throat.
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Unexplained iron deficiency anemia.
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Unintentional weight loss.
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Palpable cervical lymphadenopathy on exam.
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Persistent vomiting.
If diagnostic criteria are not met (negative):
Symptoms are unlikely to be caused by globus. Consider further assessment for other diseases, or a different functional GI disorder.
If meets diagnosis (positive):
Likely diagnosis of globus.
Management of globus may include:
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Education and patient reassurance.
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Neuromodulator.
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Behavioral therapy (e.g. cognitive behavioral therapy, hypnosis).
This calculator should only be used in patients who do not have signs or symptoms suggestive of a structural/mechanical, metabolic or systemic cause of their symptoms based on clinical history, physical exam and initial work-up.