Immune-Related Adverse Events for Renal Toxicities - Nephritis
Grades severity of nephritis secondary to immune checkpoint inhibitor therapy.
INSTRUCTIONS
Use in adult patients with elevations in creatinine levels or symptoms suggesting nephritis while on treatment with immune checkpoint inhibitors.
When to Use
Pearls/Pitfalls
Why Use
Creatinine level increase of >0.3 mg/dL; creatinine 1.5-2.0x over baseline
Creatinine 2-3x above baseline
Creatinine >3x baseline or >4.0 mg/dL; hospitalization indicated
Life-threatening consequences; dialysis indicated
Result:
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