MDCalc

World Health Organization (WHO) Diagnostic Criteria for Polycythemia Vera

Diagnoses polycythemia vera according to criteria established by the World Health Organization (WHO).

Major Criterion

Minor Criteria

<2.6 mU/mL, reference value may vary by laboratory

Diagnostic Result

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Advice
  • Evaluate results within the specific clinical context.
  • Consultation with a hematologist is recommended for patients meeting criteria for PV to determine the best course of action for hematocrit control (e.g., phlebotomy, cytoreductive therapies), thromboembolic risk assessment and prophylaxis, and symptom management.