MDCalc

Medication Regimen Complexity-Intensive Care Unit (MRC-ICU) Score

Predicts patient outcomes (mortality, length of stay), ICU complications (fluid overload), and pharmacist workload (intervention quantity and intensity) in the ICU. 

  • For each number field, enter the number of distinct medications that fall within that particular drug category.
  • Medications listed under each drug category are provided as examples; medications not listed may still belong to the category.

High Priority Medications

Amphotericin B and liposomal amphotericin B

Argatroban

Clozapine

Digoxin

Lidocaine

Continuous infusion

Lithium

Theophylline

Vancomycin

Intravenous

Warfarin

Neuromuscular blockade

Parenteral Nutrition

Managed by non-pharmacist service

Managed by clinical specialist pharmacist

Prophylaxis and FAST HUGS BID

Thromboembolic prophylaxis

Stress ulcer prophylaxis

Exclude pantoprazole infusion

Glycemic control

Subcutaneous insulin; exclude intravenous insulin

Bowel regimen

Chlorhexidine

Analgesia and Sedation

Antimicrobial Agents

Devices

Continuous renal replacement therapy

Extracorporeal membrane oxygenation (ECMO)

Intra-aortic balloon pump (IABP) / left ventricular assist device (LVAD)

Mechanical ventilation

Result:

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Advice
  • May assist in triaging the need for clinical pharmacist support and targeted interventions; a high-risk result indicates a need for closer monitoring.
  • Can be used in combination with other critical care prognostic tools (e.g., APACHE II, SOFA) to better predict the risk of inpatient mortality and prolonged ICU stays.
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