MDCalc

Wound, Ischemia, foot Infection (WIfI) Classification

Assesses severity of limb threat in patients with lower extremity disease.

W: Wound

Ulcer

Gangrene

I: Ischemia

Select one:

fI: foot Infection

Infection grade

Result:

Please fill out required fields.
Advice
  • Use the score to complement, not replace, clinical judgment; its correlation with healing time and amputation risk supports counseling and shared decision-making.
  • Schedule close follow-up and repeat calculation regularly to document trajectory.
  • Higher stages indicate an increasingly urgent need for revascularization.
Management

Society guidelines integrate both the overall stage and the individual W, I, fI grades; consult local protocols (e.g., 2019 Global Vascular Guidelines) for more detailed recommendations.

Below is a simplified summary of key recommendations:

  • Stage 1 (low risk):
    • Rarely requires revascularization.
    • Optimize risk factors (glycemic control, smoking cessation).
    • Initiate off-loading and advanced wound care.
    • Monitor for improvement, and reassess if wound healing stalls or worsens.
  • Stage 2–3 (intermediate risk):
    • Revascularization may be warranted when major tissue loss, failed healing, or significant perfusion deficits are present.
    • Obtain vascular imaging if the patient is a candidate for revascularization.
  • Stage 4 (high risk):
    • Limb is at high risk for amputation.
    • Urgently evaluate for and pursue revascularization.