MDCalc

Pediatric Fibrosis Score-Continuous (pFIB-c)

Predicts liver fibrosis risk in pediatric metabolic dysfunction–associated steatotic liver disease (MASLD).

  • This calculator is not externally validated, and as such, should be used with caution.

  • This calculator includes an input based on race, which may or may not provide better estimates. See here for more on our approach to addressing race and bias on MDCalc.

Sex

Hypertension

Black ethnicity

U/L

Result:

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Advice

This tool is not yet externally validated; continue to follow local and society guidance for pediatric MASLD fibrosis assessment.

Management

If externally validated, the score could help screen children for fibrosis risk and guide management:

  • Low risk:
    • Reinforce lifestyle and metabolic comorbidity management (weight optimization, diabetes risk reduction).
    • Repeat the score or alternative noninvasive assessment at defined intervals or with clinical change.
  • Elevated risk: May require additional workup, including imaging (e.g., transient/MR/US elastography), liver biopsy, and hepatology referral.