MDCalc

FACE DROPS

Differentiates acute Lyme disease-associated facial palsy (LDFP) from Bell palsy.

This tool is not yet externally validated.

Fever

≥38°C or ≥100.4°F

Aches

Arthralgias and/or myalgias

Cephalalgia

Headache (e.g., frontotemporal, bitemporal, and occipital) other than isolated otalgia or postauricular pain

Exhaustion

Unusual fatigue reported by the patient around time of palsy onset

Dermatomal or radicular signs

Clinical or diagnostic findings consistent with myelitis or radiculitis

Otalgia or postauricular pain

Pain in the ear or postauricular area ipsilateral to facial droop

Stiff neck

Nuchal rigidity

Result:

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Advice
  • Results of this tool should augment, not replace, clinical judgment.
  • For scores ≥5, exclude other tick-borne diseases and HIV, which can present with systemic symptoms and peripheral facial palsy.

  • Examine the external auditory canal in all patients with peripheral facial palsy to assess for vesicles diagnostic of Ramsay-Hunt syndrome.

Management

Score ≤4: Bell palsy is more likely.

  • Consider starting corticosteroids.
  • Antiviral therapy may be considered for severe cases.
  • Provide eye care.
  • Consider Lyme testing based on geography/exposure.
  • Antibiotics may be deferred absent other objective Lyme evidence.

Score 5–6: Unclear predictive value.

  • Apply clinical judgment.
  • Management of both Lyme disease and Bell palsy may be appropriate while further workup is pending.

Score ≥7: Lyme disease-associated facial paralysis is more likely.

  • Start antibiotics now.
  • Avoid corticosteroids.
  • Follow-up Lyme serology.
Critical Actions
  • Oral antibiotics are appropriate for isolated LDFP; use intravenous therapy when there are other severe neurologic manifestations.
  • Early Lyme disease can be seronegative; serology studies can support the probability of a diagnosis but should not be used to rule in/out a diagnosis.
  • Weakness restricted to the lower face should prompt consideration of a central cause of facial weakness, including stroke.