MDCalc

Immune Effector Cell Encephalopathy (ICE) Score

Assesses neurocognitive function in patients receiving CAR T-cell therapy.

Orientation

Year

Month

City

Hospital

Naming

Ability to name three objects

E.g., point to clock, pen, button

Following Commands

Ability to follow simple commands

E.g., “show me 2 fingers” or “close your eyes and stick out your tongue”

Writing

Ability to write a standard sentence

E.g., “Our national bird is the bald eagle”

Attention

Ability to count backwards from 100 by 10

Result:

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Advice

For a score <10, ICANS is likely present; lower scores indicate greater severity.

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