MDCalc

Padua Prediction Score for Risk of VTE

Determines anticoagulation need in hospitalized patients by risk of VTE.

Active cancer
Previous
Excluding superficial vein thrombosis
Reduced mobility
Already known thrombophilic condition

Recent (≤1 month) trauma and/or surgery

Elderly age (≥70 years)
Heart and/or respiratory failure
Acute and/or ischemic stroke
Acute infection and/or rheumatologic disorder
Obesity (BMI ≥30)
Ongoing hormonal treatment

Result:

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Advice

In the appropriate setting, when a physician is already considering thromboprophylaxis for a patient considered high risk for VTE, a score ≥4 has the potential to support their clinical gestalt.

Management

For patients admitted to a medical floor:

  • Score <4:
    • Low risk of VTE.
    • Thromboprophylaxis should be considered on a case-by-case basis.
  • Score ≥4:
    • High risk of VTE.
    • Thromboprophylaxis (e.g., heparin, enoxaparin) is recommended for non-pregnant patients without contraindications (major bleeding, low platelets, creatinine clearance <30 mL/min) who are >18 years.
Critical Actions
  • This tool is meant to risk stratify patients who have a potential risk for VTE, not to diagnose VTE.
  • If deemed appropriate, anticoagulation should not be withheld from patients who require it as part of the treatment for their diagnosis.
  • Prior to initiating any anticoagulant therapy, a patient’s bleeding risk should be evaluated.