Calc Function

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    • Subcategory of 'Diagnosis' designed to be very sensitiveRule Out
    • Disease is diagnosed: prognosticate to guide treatmentPrognosis
    • Numerical inputs and outputsFormula
    • Med treatment and moreTreatment
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    Attention COACH STUDY participants:

    The principal investigators of the study request that you use the official version of the modified score here.

    SSIGN Score for Renal Cell Carcinoma (RCC)

    Predicts progression of clear cell renal cell carcinoma after radical nephrectomy.
    Pearls/Pitfalls
    • The SSIGN (Stage, Size, Grade and Necrosis) score applies to clear cell renal cell carcinoma (RCC) at all stages, but not to other types of RCC.
    • Validated in multiple patient cohorts.
    pT1
    0
    pT2
    +1
    pT3a-c
    +2
    pT4
    +4
    pNx or pN0
    0
    pN1 or pN2
    +2
    M0
    0
    M1
    +4
    <5 cm
    0
    ≥5 cm
    +2
    1 or 2
    0
    3
    +1
    4
    +3
    No
    0
    Yes
    +2

    Result:

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    Next Steps
    Evidence
    Creator Insights
    Dr. Igor Frank

    About the Creator

    Igor Frank, MD, is a professor of urology at the Mayo Clinic in Rochester, MN. Currently, he is the head of the Mayo Clinic bladder removal (cystectomy) registry. His research focuses mainly on treatment and prognosis of survival in bladder and prostate cancer, though he also researches continuity and quality of care for cancer patients.

    To view Dr. Igor Frank's publications, visit PubMed

    Are you Dr. Igor Frank? Send us a message to review your photo and bio, and find out how to submit Creator Insights!
    MDCalc loves calculator creators – researchers who, through intelligent and often complex methods, discover tools that describe scientific facts that can then be applied in practice. These are real scientific discoveries about the nature of the human body, which can be invaluable to physicians taking care of patients.
    About the Creator
    Dr. Igor Frank
    Are you Dr. Igor Frank?