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    Attention COACH STUDY participants:

    The principal investigators of the study request that you use the official version of the modified score here.

    Mekhail Extension of the Motzer Score

    Predicts metastatic renal cell carcinoma survival, more accurately than the Motzer Score.
    When to Use
    Pearls/Pitfalls
    Why Use

    Patients with mRCC being considered for clinical trial enrollment.

    This score placed clinical trial subjects from the 1970s-1990s with metastatic renal cell carcinoma (mRCC) into three groups with “poor,” “intermediate,” and “favorable” survival. There are no successful validations (later studies found different predictors), and the score may not apply to patients in common practice or those receiving modern targeted therapies such as sunitinib.

    There are no validated scoring systems for predicting survival in mRCC. Using a score may help suggest categories of survival time better than clinical judgment alone.

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    Creator Insights
    Dr. Tarek Mekhail

    About the Creator

    Tarek M. Mekhail, MD, MSc, is an associate professor of medicine at the University of Central Florida and the medical director of the Thoracic Oncology Program at the Florida Hospital Cancer Institute. Dr. Mekhail has been voted one of the Best Doctors in America in 2007-2008, 2008-2009 and 2009-2010. His research focuses on novel therapies and risk stratification in lung, kidney, and head/neck cancers.

    To view Dr. Tarek Mekhail's publications, visit PubMed

    Are you Dr. Tarek Mekhail? Send us a message to review your photo and bio, and find out how to submit Creator Insights!
    MDCalc loves calculator creators – researchers who, through intelligent and often complex methods, discover tools that describe scientific facts that can then be applied in practice. These are real scientific discoveries about the nature of the human body, which can be invaluable to physicians taking care of patients.
    About the Creator
    Dr. Tarek Mekhail
    Are you Dr. Tarek Mekhail?