This is an unprecedented time. It is the dedication of healthcare workers that will lead us through this crisis. Thank you for everything you do.
COVID-19 Resource Center

      Calc Function

    • Calcs that help predict probability of a diseaseDiagnosis
    • Subcategory of 'Diagnosis' designed to be very sensitiveRule Out
    • Disease is diagnosed: prognosticate to guide treatmentPrognosis
    • Numerical inputs and outputsFormula
    • Med treatment and moreTreatment
    • Suggested protocolsAlgorithm

    Disease

    Select...

    Specialty

    Select...

    Chief Complaint

    Select...

    Organ System

    Select...

    Patent Pending

    Log In

    Show
    Forgot your password?
    Log In
    Or create a new account (it's free)

    Forgot Password?

    Enter your email address and we'll send you a link to reset your password.

    Get New Password

    Sign In Required

    To save favorites, you must log in.

    Creating an account is free, easy, and takes about 60 seconds.

    Already have an MDCalc account?

    Login to link your favorites and recently used calcs

    Show
    Forgot your password?
    Log In
    Or continue to Nuance

    Attention COACH STUDY participants:

    The principal investigators of the study request that you use the official version of the modified score here.

    HOMA-IR (Homeostatic Model Assessment for Insulin Resistance)

    Approximates insulin resistance.

    INSTRUCTIONS

    All scores are calculated in mg/dL.
    When to Use
    Pearls/Pitfalls
    Why Use

    Patients evaluated for potentially impaired glucose tolerance and diabetes.

    The score, a shortcut for estimating insulin resistance (IR), has been examined in multiple studies. Results typically show reasonable correlation between HOMA-IR and ‘clamp’ measurement, the gold standard. However agreement levels between the two, a more important gauge for individual accuracy and clinical use, are weak, suggesting more research and refinement are needed for clinical use.

    Clamp methods for measuring IR are resource intensive, invasive and time consuming, and IR can be a useful metric. An estimate of IR may help decision making.

    μIU/L
    mg/dL

    Result:

    Please fill out required fields.

    Next Steps
    Evidence
    Creator Insights
    Dr. David R. Matthews

    About the Creator

    David R. Matthews, MD, is a Professor of Diabetic Medicine at the University of Oxford. He is the Deputy co-ordinator and member of the Executive and Policy Advisory Committees of the UK Prospective Study of Diabetes (UKPDS), as well as the founder of the Oxford Health Alliance. He is currently investigating the inter-relationships between insulin resistance and beta cell function, and the effects of a low carbohydrate diet in people with and without type 2 diabetes at Churchill Hospital with the Center of Diabetes, in the United Kingdom.

    To view Dr. David R. Matthews's publications, visit PubMed

    Are you Dr. David R. Matthews? Send us a message to review your photo and bio, and find out how to submit Creator Insights!
    MDCalc loves calculator creators – researchers who, through intelligent and often complex methods, discover tools that describe scientific facts that can then be applied in practice. These are real scientific discoveries about the nature of the human body, which can be invaluable to physicians taking care of patients.
    About the Creator
    Dr. David R. Matthews
    Are you Dr. David R. Matthews?