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Glasgow-Imrie Criteria for Severity of Acute Pancreatitis

Determines severity of pancreatitis based on 8 laboratory values.

These criteria are traditionally scored with values at 48 hours after admission.

PaO₂ <59.3 mmHg (7.9 kPa)
Age >55 years
WBC >15 x 10³/µL (10⁹/L)
Calcium <8 mg/dL (2 mmol/L)
BUN >44.8 mg/dL (serum urea >16 mmol/L)
LDH >600 IU/L
Albumin <3.2 g/dL (32 g/L)
Glucose >180 mg/dL (10 mmol/L)

Result:

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Advice

The Glasgow-Imrie Criteria are comparable to the Ranson's criteria, but both have a disadvantage of requiring a 48 hours delay before they can be appropriately applied. Studies have suggested a binary cutoff at ≥3 as suggesting a significant increase in likelihood of severe pancreatitis.

Management

Local management algorithms using the criteria have been published; none are validated.

Critical Actions

The Glasgow-Imrie Criteria require using peak laboratory values and can be appropriately applied only at 48 hours after admission.

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