MDCalc

Sickle Cell RBC Exchange Volume

Estimates the volume of donor RBCs needed for RBC exchange in patients with sickle cell disease.

Note: device manufacturers may provide separate calculations for automated exchange.

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Result:

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Advice

The calculated volume of replacement RBCs may be divided by 350 mL to approximate the number of RBC units to order. Adjustments to the patient’s hematocrit may require alterations to these calculations.