Calc Function

    • Calcs that help predict probability of a diseaseDiagnosis
    • Subcategory of 'Diagnosis' designed to be very sensitiveRule Out
    • Disease is diagnosed: prognosticate to guide treatmentPrognosis
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    Patent Pending

    Maddrey's Discriminant Function for Alcoholic Hepatitis

    Suggests which patients with alcoholic hepatitis may have a poor prognosis and benefit from steroid administration.
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    Pearls/Pitfalls
    Maddrey's Discriminant Function is useful in predicting short-term prognosis but is less useful for long-term prognosis.
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    mg/dL

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    Evidence
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    Scores above 32 typically suggest poor prognosis and that these patients may be helped by steroid administration.
    Dr. Willis Maddrey

    About the Creator

    Willis Maddrey, MD, is professor of internal medicine and assistant to the president at The University of Texas Southwestern Medical Center at Dallas. Previously, he directed the liver unit at The Johns Hopkins University School of Medicine and was chairman of the Department of Medicine at Jefferson Medical College. Dr. Maddrey has authored numerous publications based on research interests in chronic viral hepatitis, drug-induced liver disease, alcohol-induced liver disease, liver transplantation, and primary biliary cirrhosis.

    To view Dr. Willis Maddrey's publications, visit PubMed