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      Calc Function

    • Calcs that help predict probability of a diseaseDiagnosis
    • Subcategory of 'Diagnosis' designed to be very sensitiveRule Out
    • Disease is diagnosed: prognosticate to guide treatmentPrognosis
    • Numerical inputs and outputsFormula
    • Med treatment and moreTreatment
    • Suggested protocolsAlgorithm

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    Patent Pending

    Modified Sequential Organ Failure Assessment (mSOFA) Score

    Predicts ICU mortality using mostly clinical variables and fewer labs (similar to SOFA Score).

    IMPORTANT

    Launched during COVID-19 crisis. COVID-19 Resource Center.

    When to Use
    Pearls/Pitfalls
    Why Use

    The mSOFA score has very similar predictive accuracy when compared to the full SOFA score and does not require significant lab testing (ABG, LFTs) to complete. It still uses the same body system components for testing, but estimates P:F ratio using O2 saturation and FiO2; it estimates liver dysfunction by looking for signs of jaundice or scleral icterus.

    The mSOFA score has been externally validated, but is certainly not as widely studied as the SOFA score.

    The mSOFA score has similar predictive accuracy without the need for laboratory tests that may not be initially indicated for a critical patient (ABG, LFTs).

    Respiratory
    >400
    0
    >315 to ≤400
    +1
    >235 to ≤315
    +2
    >150 to ≤235
    +3
    ≤150
    +4
    Liver
    No
    0
    Yes
    +3
    Cardiovascular
    No hypotension
    0
    MAP <70 mmHg
    +1
    DOPamine ≤5 or DOBUTamine (any dose)
    +2
    DOPamine >5, EPINEPHrine ≤0.1, or norEPINEPHrine ≤0.1
    +3
    DOPamine >15, EPINEPHrine >0.1, or norEPINEPHrine >0.1
    +4
    CNS
    15
    0
    13-14
    +1
    10-12
    +2
    6-9
    +3
    <6
    +4
    Renal
    <1.2
    0
    1.2-1.9
    +1
    2.0-3.4
    +2
    3.5-4.9
    +3
    >5.0
    +4
    Confirmed positive
    Suspected
    Unlikely
    Confirmed negative

    Result:

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    Next Steps
    Evidence
    Creator Insights
    Dr. Colin K. Grissom

    About the Creator

    Colin K. Grissom, MD, FASE, is the associate medical director of the Shock Trauma Intensive Care Unit and director of Critical Care Echocardiography at Intermountain Medical Center in Utah. He is also a professor of medicine at the University of Utah. Dr. Grissom’s primary research is focused on mechanical ventilation, ARDS, sepsis, and echocardiography and ultrasound for critical care.

    To view Dr. Colin K. Grissom's publications, visit PubMed

    Are you Dr. Colin K. Grissom? Send us a message to review your photo and bio, and find out how to submit Creator Insights!
    MDCalc loves calculator creators – researchers who, through intelligent and often complex methods, discover tools that describe scientific facts that can then be applied in practice. These are real scientific discoveries about the nature of the human body, which can be invaluable to physicians taking care of patients.
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