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    Radiation Biologically Effective Dose (BED) Calculator

    Calculates biologically effective dose (BED) and equivalent dose (EQD2) for cancer radiotherapy.
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    Patients undergoing radiation (to compare different fractionation regimens).

    • Note that BED is the biologically effective dose, not biologically equivalent dose.

    • EQD2 is the equivalent dose in 2-Gy fractions.

    • An α/β ratio of 10 is typically used for early-responding tissues and tumors.

    • An α/β ratio of 3 is typically used for late-responding tissues, such as normal tissue.

    • Prostate cancer has a low α/β ratio of ~1.5.

    Compares different fractionation regimens with hypofractionation or stereotactic body radiation therapy (SBRT) using a common numerical score.

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    Can also be used to determine total dose received over multiple radiation courses.

    Content Contributors
    • Neil Panjwani, MD
    Reviewed By
    • Hilary Bagshaw, MD
    About the Creator
    Dr. John F. Fowler
    Are you Dr. John F. Fowler?
    Content Contributors
    • Neil Panjwani, MD
    Reviewed By
    • Hilary Bagshaw, MD