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    Patent Pending

    Urine Anion Gap

    Detects urine acidosis for evaluation of non-gap metabolic acidosis.
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    When to Use
    Why Use
    • The patient with an unexplained non-gap metabolic acidosis.
    • The patient with a mixed metabolic acidosis.
    • Evaluation for suspected RTA.

    This simple urine test can help differentiate the causes of a non-gap metabolic acidosis (HARDUP):

    • Hyperchloremia
    • Acetazolamide, Addison’s disease
    • Renal tubular acidosis
    • Diarrhea, vomiting, ileostomies, fistulae
    • Ureteroenteric fistulae
    • Pancreatoduodenal fistulae
    mEq/L
    mEq/L
    mEq/L

    Result:

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    Next Steps
    Evidence
    Creator Insights

    Management

    Remember that hyperchloremic fluids can worsen these acidoses; consider fluids with lower chloride concentrations (like LR).

    About the Creator
    Dr. Marc Goldstein
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