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    Attention COACH STUDY participants:

    The principal investigators of the study request that you use the official version of the modified score here.

    Benzodiazepine Conversion Calculator

    Provides equivalents between different benzodiazepines.

    IMPORTANT

    This calculator should be used as a reference for oral benzodiazepine conversions. Equipotent benzodiazepine doses are reported as ranges due to paucity of literature supporting exact conversions, thus reported ranges are based on expert opinion and clinical experience published in psychiatric literature.

    INSTRUCTIONS

    Do not use to calculate initial dose for a benzo-naïve patient.

    When to Use
    Pearls/Pitfalls

    Intended for use when interchanging benzodiazepines and should not be used to help calculate an initial dose for a benzodiazepine naïve patient.

    • Durations of action:

      • Very short acting: <6 hours.

      • Short acting: 6-12 hours (ALPRAZolam, oxazepam, triazolam).

      • Intermediate acting: 12-24 hours (LORazepam, temazepam).

      • Long acting: >24 hours (chlordiazePOXIDE, diazePAM, clonazePAM).

    • This calculator does not account for age, organ function, and inter-patient variability that may alter the pharmacokinetics, peak effect, and duration of action.

    • Selecting doses on the lower end of the reported range may result in lower risk of unwanted oversedation.

    • Dosing conversions may not be adequate when treating such conditions as status epilepticus or alcohol withdrawal. Disease-state specific guidelines should be utilized.  

    ALPRAZolam (Xanax)
    ChlordiazePOXIDE (Librium)
    DiazePAM (Valium)
    ClonazePAM (KlonoPIN)
    LORazepam (Ativan)
    Oxazepam (Serax)
    Temazepam (Restoril)
    Triazolam (Halcion)
    mg
    ALPRAZolam (Xanax)
    ChlordiazePOXIDE (Librium)
    DiazePAM (Valium)
    ClonazePAM (KlonoPIN)
    LORazepam (Ativan)
    Oxazepam (Serax)
    Temazepam (Restoril)
    Triazolam (Halcion)

    Result:

    Please fill out required fields.

    Next Steps
    Evidence
    Creator Insights
    OTHER

    About the Creator

    Other creator.

    Content Contributors
    • Jenny L. Koehl, PharmD
    About the Creator
    OTHER
    Also from MDCalc...
    Content Contributors
    • Jenny L. Koehl, PharmD