MDCalc

Acute Gout Diagnosis Rule

Risk stratifies for gout vs non-gout arthritis and helps determine which patients benefit most from joint aspiration.

Male sex
Previous patient-reported arthritis attack
Onset within 1 day
Joint redness
1st metatarsophalangeal joint involvement
Hypertension or ≥1 cardiac diseases
Angina, MI, CHF, Stroke/TIA, PVD
Serum uric acid > 5.88 mg/dL (0.35 mmol/L)

Result:

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Advice

The authors provide several recommendations based on a patient's score:

  • ≤4 points: Unlikely gout. Other causes of monoarthritis should be considered, for example: pseudogout, septic arthritis, reactive arthritis, psoriatic, rheumatoid, or osteoarthritis.
  • 4-8 points: These patients are most likely to benefit from joint aspiration and fluid analysis for urate crystals.
  • ≥8 points: Gouty arthritis is very likely, and empiric gout medications can be started as opposed to more generic arthritis treatments (like NSAIDs).
Management
  • Gout flares are often treated with some combination of steroids, NSAIDS (classically, indomethacin), opioids for extreme pain, and colchicine, depending on a patient's age and other risk factors for complications.
  • After the initial flare, patients may benefit from urate-lowering therapies like allopurinol.