MDCalc

Asymptomatic Myeloma Prognosis

Predicts risk of progression of asymptomatic (smoldering) multiple myeloma to active myeloma or amyloidosis.

Bone marrow plasmacytosis
Average % from bone marrow aspirate and core biopsy
Serum monoclonal protein, g/dL
On serum protein electrophoresis

Result:

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Advice

Patients with smoldering or asymptomatic MM are currently observed. However, clinical trials should be sought for appropriate patients given the rapid progress in development of novel active agents.