MDCalc

Hour-Specific Risk for Neonatal Hyperbilirubinemia

Predicts risk of hyperbilirubinemia in neonates.

  • Use in otherwise healthy neonates ≥35 weeks gestational age (GA) at the time of discharge. Do not use in neonates with positive direct Coombs test, or in those requiring phototherapy before 60 hours of age. Do not use to determine need for exchange transfusion.
  • The recommendations listed here for starting phototherapy are based on AAP guidelines. Always use clinical judgment, in addition to considering evidence-based clinical guidelines, in making treatment decisions. 

hours

Gestational age, weeks

Optional, for phototherapy recommendations based on AAP guidelines

Result:

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Advice

  • The risk calculator is one of two clinical options recommended by the AAP for risk assessment (either clinical risk factors alone or in combination with the risk calculator).

  • Most important clinical risk factors to consider include: breastfeeding, GA <38 weeks, significant jaundice in a sibling (defined as requiring phototherapy), and jaundice noted before discharge (Newman 2000).

Management
  • An infant whose predischarge total serum bilirubin is in the low risk zone is at very low risk for developing severe hyperbilirubinemia.

  • Appropriate follow up after discharge must be ensured regardless of method of risk assessment used.

Infant discharged

Should be seen by age

Before 24 hrs

72 hrs

Between 24 and 48 hrs

96 hrs

Between 48 and 72 hrs

120 hrs

From AAP guidelines.

Critical Actions

Clinical judgment should guide follow up. Neonates at higher risk and with clinical risk factors may be followed earlier.