Management of Hyperbilirubinemia in the Newborn Infant 35 or More Weeks of Gestation Pediatrics. 2004;114(1):297-316.

Bhutani VK, Johnson L, Sivieri EM. Predictive ability of a predischarge hour-specific serum bilirubin for subsequent significant hyperbilirubinemia in healthy term and near-term newborns. Pediatrics. 1999;103(1):6-14.

Newman TB, Xiong B, Gonzales VM, Escobar GJ. Prediction and prevention of extreme neonatal hyperbilirubinemia in a mature health maintenance organization. Arch Pediatr Adolesc Med. 2000;154(11):1140-7.

Stevenson DK, Fanaroff AA, Maisels MJ, et al. Prediction of hyperbilirubinemia in near-term and term infants. Pediatrics. 2001;108(1):31-9.

Dr. Vinod K. Bhutani

calc_output = [];
var age = parseFloat(age);
var tsb = parseFloat(tsb);
var factor = parseFloat(factor) || 0;
var gest = parseFloat(gest) || 0;

if(UOMSYSTEM == false){
  tsb = tsb/17.1;
}

age = age.toFixed(0);

var risk, prob;

var forty = [4.0,
4.0,
4.2,
4.3,
4.4,
4.5,
4.5,
4.6,
4.7,
4.8,
4.9,
4.9,
5.0,
5.2,
5.3,
5.5,
5.6,
5.8,
6.0,
6.1,
6.3,
6.5,
6.7,
6.9,
7.0,
7.2,
7.4,
7.6,
7.8,
7.9,
7.9,
8.0,
8.1,
8.2,
8.4,
8.5,
8.6,
8.7,
8.8,
8.9,
8.9,
9.0,
9.1,
9.2,
9.3,
9.4,
9.4,
9.5,
9.6,
9.7,
9.9,
10.0,
10.1,
10.3,
10.4,
10.5,
10.7,
10.8,
10.9,
11.1,
11.2,
11.2,
11.3,
11.3,
11.3,
11.4,
11.4,
11.4,
11.5,
11.5,
11.5,
11.6,
11.6,
11.7,
11.7,
11.8,
11.9,
11.9,
12.0,
12.1,
12.1,
12.2,
12.3,
12.3,
12.4,
12.4,
12.5,
12.5,
12.5,
12.6,
12.6,
12.7,
12.7,
12.7,
12.8,
12.8,
12.8,
12.9,
12.9,
12.9,
13.0,
13.0,
13.0,
13.1,
13.1,
13.1,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.2,
13.3,
13.3,
13.3,
13.3,
13.3,
13.3,
13.3,
13.3,
13.3,
13.3,
13.4,
13.4,
13.4,
13.4,
13.4,
13.4,
13.4,
13.4,
13.4,
13.4];

var seventy_fifth = [5.09,
5.19, 
5.39, 
5.49, 
5.59, 
5.69, 
5.6,
5.7,
5.8,
6.0,
6.1,
6.3,
6.4,
6.6,
6.7,
6.9,
7.0,
7.2,
7.5,
7.7,
8.0,
8.2,
8.5,
8.7,
8.9,
9.2,
9.4,
9.7,
9.9,
10.0,
10.1,
10.1,
10.2,
10.4,
10.5,
10.7,
10.8,
11.0,
11.1,
11.3,
11.4,
11.6,
11.7,
11.9,
12.0,
12.2,
12.3,
12.5,
12.6,
12.7,
12.7,
12.8,
12.9,
12.9,
13.0,
13.1,
13.1,
13.2,
13.3,
13.3,
13.4,
13.5,
13.6,
13.7,
13.8,
13.9,
14.0,
14.1,
14.2,
14.3,
14.4,
14.5,
14.6,
14.7,
14.7,
14.8,
14.8,
14.9,
14.9,
15.0,
15.0,
15.1,
15.1,
15.2,
15.2,
15.2,
15.3,
15.3,
15.3,
15.3,
15.4,
15.4,
15.4,
15.4,
15.5,
15.5,
15.5,
15.5,
15.6,
15.6,
15.6,
15.6,
15.7,
15.7,
15.7,
15.7,
15.8,
15.8,
15.8,
15.8,
15.8,
15.7,
15.7,
15.7,
15.7,
15.7,
15.6,
15.6,
15.6,
15.6,
15.6,
15.5,
15.5,
15.5,
15.5,
15.5,
15.4,
15.4,
15.4,
15.4,
15.3,
15.3,
15.3,
15.3,
15.3,
15.3,
15.3,
15.3,
15.3,
15.3,
15.3,
15.3,
15.3,
15.4,
15.4,
15.4,
15.4,
15.4,
15.4,
15.4,
15.4,
15.4,
15.4,
15.4,
15.4,
15.4,
15.4];

var ninty_fifth = [7.0,
7.1,
7.2,
7.2,
7.3,
7.3,
6.9,
7.2,
7.4,
7.5,
7.6,
7.7,
7.8,
8.1,
8.4,
8.6,
8.9,
9.2,
9.4,
9.7,
10.0,
10.3,
10.5,
10.8,
11.1,
11.4,
11.6,
11.9,
12.2,
12.3,
12.3,
12.4,
12.5,
12.7,
12.8,
13.0,
13.2,
13.3,
13.5,
13.7,
13.8,
14.0,
14.2,
14.3,
14.5,
14.7,
14.8,
15.0,
15.2,
15.2,
15.3,
15.4,
15.4,
15.5,
15.5,
15.6,
15.7,
15.7,
15.8,
15.9,
15.9,
16.0,
16.1,
16.1,
16.2,
16.3,
16.3,
16.4,
16.5,
16.5,
16.6,
16.6,
16.7,
16.8,
16.8,
16.9,
16.9,
17.0,
17.1,
17.1,
17.2,
17.2,
17.3,
17.3,
17.4,
17.4,
17.4,
17.4,
17.4,
17.4,
17.5,
17.5,
17.5,
17.5,
17.5,
17.5,
17.5,
17.5,
17.5,
17.5,
17.5,
17.5,
17.6,
17.6,
17.6,
17.6,
17.6,
17.6,
17.6,
17.6,
17.6,
17.6,
17.5,
17.5,
17.5,
17.5,
17.5,
17.5,
17.5,
17.4,
17.4,
17.4,
17.4,
17.4,
17.4,
17.4,
17.4,
17.3,
17.3,
17.3,
17.3,
17.3,
17.3,
17.3,
17.3,
17.4,
17.4,
17.5,
17.5,
17.5,
17.6,
17.6,
17.6,
17.7,
17.7,
17.7,
17.8,
17.8,
17.9,
17.9,
17.9,
18.0,
18.0,
18.0,
18.1,
18.1,
18.2];

if (tsb < forty[age-12]) {
	risk = 'Low';
	prob = '0';
} else if (tsb >= forty[age-12] && tsb <= seventy_fifth[age-12]) {
	risk = 'Low-intermediate';
	prob = '2.2';
} else if (tsb > seventy_fifth[age-12] && tsb < ninty_fifth[age-12]) {
	risk = 'High-intermediate';
	prob = '12.9';
} else if (tsb >= ninty_fifth[age-12]) {
	risk = 'High';
	prob = '39.5';
}

if (gest > 0) {
    var category;
    if (gest == 1 && factor == 1) {
        category = 'Low';
    } else if (gest == 1 && factor == 2) {
        category = 'Medium';
    } else if (gest == 2 && factor == 1) {
        category = 'Medium';
    } else if (gest == 2 && factor == 2) {
        category = 'High';
    }

    var low = [9.1, 9.3, 9.5, 9.8, 10.0, 10.2, 10.4, 10.6, 10.8, 11.1, 11.3, 11.5, 11.7, 11.9, 12.0, 12.2, 12.3, 12.5, 12.7, 12.8, 13.0, 13.1, 13.3, 13.4, 13.6, 13.7, 13.9, 14.0, 14.2, 14.3, 14.5, 14.6, 14.7, 14.9, 15.0, 15.2, 15.3, 15.4, 15.5, 15.6, 15.7, 15.8, 16.0, 16.1, 16.2, 16.3, 16.4, 16.5, 16.6, 16.7, 16.8, 16.9, 17, 17.1, 17.2, 17.2, 17.3, 17.4, 17.5, 17.6, 17.7, 17.8, 17.9, 18, 18.1, 18.2, 18.3, 18.4, 18.5, 18.6, 18.7, 18.8, 18.9 , 19, 19.1, 19.2 , 19.2, 19.3, 19.4, 19.5, 19.6, 19.7, 19.7, 19.8, 19.9, 20, 20, 20.1, 20.1, 20.2, 20.3, 20.3, 20.4, 20.4, 20.5, 20.5, 20.6, 20.6, 20.7 , 20.7, 20.7, 20.8, 20.8, 20.8, 20.9, 20.9, 20.9, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21, 21];
    var medium = [7.7, 7.9, 8.1, 8.3, 8.4, 8.6, 8.8, 9.0, 9.2, 9.4, 9.5, 9.7, 9.9, 10.1, 10.2, 10.4, 10.5, 10.7, 10.8, 11.0, 11.1, 11.3, 11.4, 11.6, 11.7, 11.8, 11.9, 12.1, 12.2, 12.3, 12.4, 12.5, 12.6, 12.8, 12.9, 13.0, 13.1, 13.2, 13.4, 13.5, 13.6, 13.7, 13.9, 14, 14.1, 14.2, 14.4, 14.5, 14.6, 14.7, 14.8, 14.8, 14.9, 15, 15.1, 15.1, 15.2, 15.3, 15.4, 15.4, 15.5, 15.6, 15.7, 15.8, 15.9, 16, 16.1, 16.1, 16.2, 16.3, 16.4, 16.5, 16.6, 16.7, 16.8, 16.8, 16.9, 17, 17.1, 17.1, 17.2, 17.3, 17.4, 17.4, 17.5, 17.5, 17.6, 17.6, 17.7, 17.7, 17.8, 17.8, 17.8, 17.9, 17.9, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18, 18];
    var high = [6.0, 6.2, 6.3, 6.5, 6.7, 6.8, 7.0, 7.2, 7.3, 7.5, 7.7, 7.8, 8.0, 8.1, 8.3, 8.4, 8.5, 8.7, 8.8, 8.9, 9.1, 9.2, 9.3, 9.5, 9.6, 9.8, 9.9, 10.1, 10.2, 10.4, 10.5, 10.7, 10.8, 11.0, 11.1, 11.3, 11.4, 11.5, 11.6, 11.7, 11.8, 11.9, 12.0, 12, 12.1, 12.2, 12.3, 12.4, 12.5, 12.6, 12.7, 12.8, 12.9, 13, 13.1, 13.1, 13.2, 13.3, 13.4, 13.5, 13.6, 13.7, 13.7, 13.8, 13.8, 13.9, 13.9, 14, 14, 14.1, 14.1, 14.2, 14.2, 14.2, 14.3, 14.3, 14.3, 14.3, 14.4, 14.4, 14.4, 14.4, 14.5, 14.5, 14.5, 14.5, 14.6, 14.6, 14.7, 14.7, 14.8, 14.8, 14.8, 14.9, 14.9, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15, 15];

    var rec;
    if (category == 'Low') {
        if (tsb < low[age-12]) {
            rec = 'No';
        } else {
            rec = 'Yes';
        }
    } else if (category == 'Medium') {
        if (tsb < medium[age-12]) {
            rec = 'No';
        } else {
            rec = 'Yes';
        }
    } else if (category == 'High') {
        if (tsb < high[age-12]) {
            rec = 'No';
        } else {
            rec = 'Yes';
        }
    }

    if (rec == 'Yes') {
        var msg = 'Bilirubin threshold is exceeded; start phototherapy as per AAP phototherapy guidelines';
    } else if (rec == 'No') {
        var msg = 'Do not need to start phototherapy as per AAP phototherapy guidelines';
    }

}



//results
calc_output.push({
    name: 'mini',
    value: risk,
    value_text: '',
    message: 'Hour-specific TSB risk zone'
});
calc_output.push({
    name: 'Score',
    value: risk,
    value_text: '',
    message: 'Hour-specific TSB risk zone'   
    });
calc_output.push({
    name: 'risk1',
    value: prob, 
    value_text: '%',
    message: 'Probability of subsequent neonatal hyperbilirubinemia'
});
if (gest > 0) {
    calc_output.push({
        name: 'risk1',
        value: rec, 
        value_text: '',
        message: 'Start phototherapy?<br/><br/>' + msg
    });
}

Hour-Specific Risk for Neonatal Hyperbilirubinemia

gest

factor

<p>Predicts risk of hyperbilirubinemia in neonates.</p>

Neonatal Hyperbilirubinemia Risk

The Hour-Specific Risk for Neonatal Hyperbilirubinemia predicts risk of hyperbilirubinemia in newborns based on total serum bilirubin (TSB) measurement.

Bilirubin

age_neonate

Rebound Hyperbilirubinemia Risk Score

HAS-BLED Score

VACO Index

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Listen to the VACO co-creators break down how to use VACO\, what it does\, and what it doesn’t.

Calc Function